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  • Restylane® Defyne Washington DC Restylane® Defyne Washington DC
  • Restylane® Defyne Washington DC Before and After Restylane® Defyne Washington DC Before and After
  • Restylane® Defyne Washington DC Before and After Restylane® Defyne Washington DC Before and After

Restylane® Defyne Washington DC

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Quick Overview

We offer Restylane® Defyne in Washington DC at Cultura Dermatology & Laser Center, 5301 Wisconsin Avenue NW Washington, DC 20015.


See additional Filler before and after photos.

What is Restylane Defyne?

If you know anything about cosmetic treatments, you know that dermal fillers are one of the most effective, flexible and affordable treatments you can get. 

The new Restylane products of Refyne and Defyne are innovative iterations upon this product, with slight differences in their respective formulations to provide different results.

Why We Volumize Our Face

At the age of 25, our face stops producing the collagen that keeps us looking perpetually young. Even worse, at age 30, we start losing enough volume in collagen that the fissures that have been forming the last years start becoming noticeable wrinkles.
That's where dermal fillers come in.
By simply replacing the volume in the face with substances the body already produces--such as hyaluronic acid--we can bring back the volume in the face that we once had.
In fact, we can even add volume to places that previously were lacking in volume, sometimes due to genetic predispositions.
The fact that hyaluronic acid is a substance that our body loves, because it keeps our skin moist and helps deliver nutrition, makes it an even better deal for our bodies.
Restylane Refyne and Defyne are even better improvements upon this.

Flexibility and Support

Restylane Defyne uses XpresHAN technology to both provide flexibility and support to our faces. Essentially, the hyaluronic acid that is normally used in filler is held together with a cross-linking technology like a semi-taut net.
The end result is that our faces are able to express their full range of emotion, but still having support from the volumizing filler.
Thus, deeper wrinkles are avoided, but there's no loss of expression. Between Restylane Defyne and Refyne, Defyne offers greater support and is of more use to ameliorate deeper wrinkles.

Additional Information

  • Helps smooth out deep laugh lines (nasolabial folds and marionette lines).
  • Helps restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.

How is Restylane® Defyne different?

As we age, our skin loses elasticity and the lines that run from the sides of the nose toward the corners of the mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) become more pronounced. Restylane Defyne is crafted with XpresHAn Technology™ to correct these deepened lines.3† The unique cross-linking of the gel in Restylane Defyne is also designed to help support your facial expressions—for natural-looking results that help maintain your natural movement.1,2

Are there any reasons why I should not use products within the Restylane® family? (Contraindications)

To ensure a safe procedure, your doctor will talk to you about your medical history to determine if you are an appropriate candidate for treatment. You should not use products within the Restylane family if:

  • You have severe allergies with a history of severe reactions (anaphylaxis)
  • You are allergic to lidocaine or to any of the gram-positive bacterial proteins used to make hyaluronic acid
  • You are prone to bleeding or have been diagnosed with a bleeding disorder
  • Tell your doctor if you are breastfeeding, pregnant, or trying to become pregnant. The safety of these products for use during pregnancy, or in women who are breastfeeding, has not been studied
  • Restylane, Restylane-L, Restylane® Lyft with Lidocaine, Restylane Refyne and Restylane Defyne are intended to treat facial wrinkles and folds, such as nasolabial folds. Restylane and Restylane-L are also intended for lip enhancement. Treatments in other areas of the face have not been evaluated in clinical studies.
  • The safety and effectiveness of Restylane® Silk for areas other than the lips and perioral area have not been evaluated in clinical studies
  • Tell your doctor if you have any history of scarring, particularly thick and stiff scars, or any pigmentation (skin color) disorders. These side effects can occur with hyaluronic acid fillers in general.
  • Tell your doctor if you are planning other laser treatments or a chemical peel, as there is a possible risk of inflammation at the treatment site if these procedures are performed after treatment
  • Patients who experience skin injury near the site of injection with these products may be at a higher risk for side effects
  • Tell your doctor if you are on any medications to decrease your body’s immune response (immunosuppressive therapy). Using these medications may increase your risk of bruising or bleeding at the gel injection site.
  • Tell your doctor if you are using any “blood thinners” such as aspirin, warfarin, or any other medications that affect bleeding. Using these medications may increase your risk of bruising or bleeding at the gel injection site.
  • The use of these products on gel injection sites with skin sores, pimples, rashes, hives, cysts, or infections should be postponed until healing is complete. Use of product in these areas could delay healing or make your skin problems worse.

What are the possible side effects?

The most commonly observed side effects are swelling, redness, pain, bruising, headache, tenderness, lump formation, and itching at the injection site. These are typically mild in severity and typically resolve in less than 7 days in nasolabial folds and less than 14 days in lips. Serious but rare side effects include delayed onset infections, recurrence of herpetic eruptions, and superficial necrosis at the injection site.

One of the risks with using this product is unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious, and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin.

As with all skin injection procedures, there is a risk of infection.

Treatment TypeFiller, Injectables
Treatment Problem or ConditionFacial Volume Loss, Fine Lines, Wrinkles
Skin TypeAging Skin
Size1 cc syringe

Restylane Defyne is indicated for injection into the mid-to-deep dermis for correction of
moderate to severe, deep facial wrinkles and folds (such as nasolabial folds) in patients
over the age of 21.


  • Restylane Defyne is contraindicated for patients with severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies.
  • Restylane Defyne may contain trace amounts of gram-positive bacterial proteins and is contraindicated for patients with a history of allergies to such material.
  • Restylane Defyne contains lidocaine and is contraindicated for patients with a history of allergies to such material.

Restylane® Defyne is a sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colorless, and homogeneous soft hyaluronic acid gel with a high lifting capacity. The product has a sodium hyaluronate concentration of 20 mg/mL in phosphate buffered saline at pH 7 and contains 3 mg/mL lidocaine hydrochloride.

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