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  • Restylane® Refyne Washington DC Restylane® Refyne Washington DC
  • Restylane® Refyne Washington DC Before and After Restylane® Refyne Washington DC Before and After
  • Restylane® Refyne Washington DC Before and After Restylane® Refyne Washington DC Before and After

Restylane® Refyne Washington DC

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Quick Overview

We offer Restylane® Refyne in Washington DC at Cultura Dermatology & Laser Center, 5301 Wisconsin Avenue NW Washington, DC 20015.


See additional Filler before and after photos.


What is Restylane Refyne?

If you know anything about cosmetic treatments, you know that dermal fillers are one of the most effective, flexible and affordable treatments you can get.

The new Restylane products of Refyne and Defyne are innovative iterations upon this product, with slight differences in their respective formulations to provide different results.

The Miracle of Hyaluronic Acid

Hyaluronic Acid might be a scary name for a substance, but don't be alarmed. There's plenty of it in your body.
And not only is it keeping your skin moist, it's also helping deliver nutrients to that skin to ensure healthy collagen production.
So it's no wonder that we use it as a dermal filler. Many consumers think fillers are just static substances used to volumize the face, but that's not true.
When hyaluronic acid is used as an injectable, it facilitates the processes that keep the skin looking radiant and healthy.
So what does Refyne and it's patented XpresHAN technology add?

XpresHAN? What's that?

While dermal fillers already make the face look more radiant and youthful in a natural looking way, Refyne takes it to the next level. By using cross-linking XpresHAN technology, the filler, made up of hyaluronic acid, is 'held together' like a flexible net.
Thus it provides support to your face, but also stays flexible enough to allow a full and natural range of emotion. Because dermal fillers are oftentimes used by individuals who exacerbate wrinkles due to highly expressive faces, this is especially useful.
Now you can show that thousand watt smile in all its radiance, without the fear of smile lines that usually come with a theatrical face.
Between Refyne and Defyne, Refyne is the more flexible of the two, while Defyne provides more support.

Additional Information

  • Helps soften laugh lines (nasolabial folds and marionette lines).
  • Helps restore a more youthful, natural-looking appearance, while helping you maintain your natural expressions.

What is Restylane® Refyne?

As skin loses elasticity with age, the lines that run from the sides of your nose toward the corners of your mouth (nasolabial folds) and the lines that run from the corner of your mouth toward the chin (marionette lines) appear more noticeable. Restylane Refyne is a specifically formulated hyaluronic acid dermal filler made with XpresHAn Technology™ that helps correct these lines for a more natural look to your face.3† The unique cross-linking of the gel in Restylane Refyne is also designed to help support your natural expression—for real-life results that help maintain natural movement when you're smiling, frowning and even puckering up.1,2

Are there any reasons why I should not use products within the Restylane® family? (Contraindications)

To ensure a safe procedure, your doctor will talk to you about your medical history to determine if you are an appropriate candidate for treatment. You should not use products within the Restylane family if:

  • You have severe allergies with a history of severe reactions (anaphylaxis)
  • You are allergic to lidocaine or to any of the gram-positive bacterial proteins used to make hyaluronic acid
  • You are prone to bleeding or have been diagnosed with a bleeding disorder
  • Tell your doctor if you are breastfeeding, pregnant, or trying to become pregnant. The safety of these products for use during pregnancy, or in women who are breastfeeding, has not been studied
  • Restylane, Restylane-L, Restylane® Lyft with Lidocaine, Restylane Refyne and Restylane Defyne are intended to treat facial wrinkles and folds, such as nasolabial folds. Restylane and Restylane-L are also intended for lip enhancement. Treatments in other areas of the face have not been evaluated in clinical studies.
  • The safety and effectiveness of Restylane® Silk for areas other than the lips and perioral area have not been evaluated in clinical studies
  • Tell your doctor if you have any history of scarring, particularly thick and stiff scars, or any pigmentation (skin color) disorders. These side effects can occur with hyaluronic acid fillers in general.
  • Tell your doctor if you are planning other laser treatments or a chemical peel, as there is a possible risk of inflammation at the treatment site if these procedures are performed after treatment
  • Patients who experience skin injury near the site of injection with these products may be at a higher risk for side effects
  • Tell your doctor if you are on any medications to decrease your body’s immune response (immunosuppressive therapy). Using these medications may increase your risk of bruising or bleeding at the gel injection site.
  • Tell your doctor if you are using any “blood thinners” such as aspirin, warfarin, or any other medications that affect bleeding. Using these medications may increase your risk of bruising or bleeding at the gel injection site.
  • The use of these products on gel injection sites with skin sores, pimples, rashes, hives, cysts, or infections should be postponed until healing is complete. Use of product in these areas could delay healing or make your skin problems worse.

What are the possible side effects?

The most commonly observed side effects are swelling, redness, pain, bruising, headache, tenderness, lump formation, and itching at the injection site. These are typically mild in severity and typically resolve in less than 7 days in nasolabial folds and less than 14 days in lips. Serious but rare side effects include delayed onset infections, recurrence of herpetic eruptions, and superficial necrosis at the injection site.

One of the risks with using this product is unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious, and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin.

As with all skin injection procedures, there is a risk of infection.

Treatment TypeNo
Treatment Problem or ConditionNo
Skin TypeNo
Size1 cc syringe

Restylane® Refyne is for mid-to-deep injection into the facial tissue for the correction of moderate to severe facial wrinkles and folds, such as nasolabial folds, in patients over the age of 21.


  • Restylane Refyne is contraindicated for patients with severe allergies manifested by a history of anaphylaxis or history or presence of multiple severe allergies.
  • Restylane Refyne may contain trace amounts of gram-positive bacterial proteins and is contraindicated for patients with a history of allergies to such material. 
  • Restylane Refyne contains lidocaine and is contraindicated for patients with a history of allergies to such material.

Restylane® Refyne is a sterile, biodegradable, viscoelastic, non-pyrogenic, clear, colorless, and homogeneous soft hyaluronic acid gel with a moderate lifting capacity. The product has a sodium hyaluronate concentration of 20 mg/mL in phosphate buffered saline at pH 7 and contains 3 mg/mL lidocaine hydrochloride.

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